Tag Archives: Bangalore

Indian scientists close to a new drug for blood cancer

Bhavya Khullar

Members of the research team : Sathees Raghvan and Supriya Vartak

New Delhi: A group Indian scientists has a found a new compound that effectively kills leukemic cancer cells.

Codenamed5g, the new drug can kill over 70 percent blood cancer cells in petri dish in 48 hours at an extremely low concentration. It did not affect healthy blood cells, which signifies that is toxic to cancer cells. “After treating with 5g cancer cells either entered cell death or revertedback to normal cell cycle”, say scientists who have tested this new compound.

The new compound has been found to be most effective in leukemic cells, while other cancer cell lines like colorectal and cervical showed less effect. It accumulates death-inducing reactive oxygen species in cancer cells leading to breaks in DNA, which ultimately causes cell death.

“We are working with Mysuru University to improve its efficacy. We believe that it has the potential to be developed as an anti-leukemic agent”, says Professor Sathees Raghavan, a member of the research team at Indian Institute of Science, Bangalore. The research findings have been published in journal Scientific Reports.

The drug has been tested in laboratory animals. Daily doses of 5g for two weeks reduced the size of tumor in mice. It was non-toxic and moderately increased the life span of diseased mice. The tumor regression was incomplete, because of which,the scientists suggest that 5g needs combinational compounds to increase its efficiency. “We have identified a novel inhibitor of cell cycle and provide evidence at proof of principle level that 5g can be developed as a potent anti-cancer molecule for chemotherapy”, they say.

This study was done at the Indian Institute of Science in Bangalore, University of Mysore inMysuru, and Institute of Bioinformatics and Applied Biotechnology in Bangalore. It was supported by IISc-Department of Biotechnology partnership. The research team included Mahesh Hegde, Supriya VVartak, Chandagirikoppal V Kavitha, Hanumappa Ananda, Doddakunche S Prasanna, Vidya Gopalakrishnan, Bibha Choudhary, Kanchugarakoppal, S Rangappa, and Sathees C Raghavan.

India Science Wire

Author’s twitter handle: BhavyaSc

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ESIC officer convicted, gets 4-year sentence in a bribery case

Newsroom24x7 Staff

cbiNew Delhi: The Principal Special Judge for CBI Cases in Bangalore has convicted N. Anand Kumar, former Deputy Director, ESIC, Sub- Regional Office at Peenya, Bangalore (North) and sentenced him to undergo four years simple imprisonment with fine of Rs.35,000 in a bribery case.

CBI had registered a case against Kumar under Sections 7 and 13(2) read with Section 13(1)(d) of Prevention of Corruption Act, 1988 on the allegations he had issued claim Notices to the complainant in this case in 2013 with exorbitant and illegitimate demands under false pretext to the tune of Rs. 9.5 million.

The complainant met the accused when he came to attend two Court cases filed by ESI during 2012 and 2013 and enquired about the orders of 19 February 2014 passed by him against his (complainant’s) company. Kumar responded by telling the complainant to go in appeal before the Director who can waive the demand. The accused also demanded a sum of Rs. 25000 from the complainant for closing all the issues and Court cases pending against his company. The complainant approached CBI and filed a complaint against the accused. CBI laid a trap and Kumar was caught red-handed while accepting a bribe of Rs. 25,000 from the complainant. A chargesheet was filed against the accused on 16 December 2014.

The Trial Court found the accused guilty and convicted him.

3-year Rigorous Imprisonment for a Naib Tehsildar and others

The Special Judge, CBI Cases, Panchkula (Haryana) has convicted and ordered 3-year Rigorous Imprisonment for Jai Pal Singh, ex-Naib Tehsildar, working in the Land Acquisition Office at Faridabad; Dhanpat Singh Ranga, the then Assistant District Attorney; Mahesh Chand Sharma, then Section Officer; Narsingh Dass, then Kanungo and one year RI to Yatinder Singh, Advocate with total fine of Rs.6,30,000 under Sections 120-B, 409, 420, 471 of Indian Penal Code (IPC) & 13(2) read with 13(1)(d) & 13(1)(c) of Prevention of Corruption Act, 1988.

CBI had registered a case on 2 March 2005 against those who have now been convicted. The High Court of Punjab and Haryana had transferred the Case to CBI which was earlier registered (FIR No.13/98, 15 December 1998) by the State Vigilance Bureau at Gurgaon on the allegations of defrauding the public exchequer of Rs.7,43,477.

After investigation, a charge sheet was filed on 16 October 2006 in the court of Special Judge, CBI cases at Panchkula in Haryana against Jai Pal Singh and others. Charges in this case were framed on 24 September 2007.

The Trial Court has acquitted two advocates, who were accused in this case.

5 year rigorous imprisonment for two officers of Income Tax department

Newsroom24x7 Staff

cbiNew Delhi: The Special Judge for CBI Cases in Bangalore has convicted Dhirendra Kumar Jha, former Additional Commissioner of Income Tax, and U.A. Chandramouli, a former Deputy Commissioner of Income Tax at Bangalore and sentenced them to undergo five years rigorous imprisonment with fine of Rs.7.50 lakh each for causing loss of over Rs.4.16 crore to the Government Exchequer.

CBI had registered a case on 26 September 2008 against Chandramouli, then Deputy Commissioner of Income Tax at Bangalore and Chairman of M/s. Children’s Educational Society, J.P. Nagar, Bangalore under Sections 120-B, 218, 420 of Indian Penal Code (IPC) and Section 13(2) read with 13(1)(d) of Prevention of Corruption Act, 1988. After completion of investigation, a charge sheet was filed on 21 April 2010 against Chandramouli, Chairman of M/s. Children’s Educational Society and Dhirendra Kumar Jha, the then Addl. Commissioner of Income Tax at Bangalore alleging that the public servants had entered into a criminal conspiracy with the Chairman of the society in the assessment of income tax of his NGO and fraudulently returned a key document reflecting financial transactions of the Society with a Bangalore based construction company without retaining the copies on record. The assessment of M/s. Children’s Education Society for the financial year 2003-04 was carried out on 22 December 2006 by the the convicted officials of Income Tax Department, ignoring the aforesaid transactions and reducing the tax liability which had caused a loss of over Rs.4.16 crore to the Income Tax Department(Govt. of India) and corresponding gain to the assessee. The Chairman of M/s. Children’s Educational Society, J.P. Nagar, Bangalore expired during the trial. Hence, the case against him was abetted.

The Trial Court found both the Additional and Deputy Commissioner of Income Tax guilty and convicted them.

On the beastly stripping of a Tanzanian lady student

Jamsheed Rizwani

Bangalore's shameHorrified by the bestial attack on a Tanzanian lady student in Bengalaru….. Xenophobic and racist attitudes seem to sink root deeply in the garden city which is no longer a garden but a maelstrom of cars, buildings and teeming millions flocking to cash in on the IT mega rush…….The city which was once a peaceful and friendly metropole has been transformed into a nightmare of traffic, of communal problems and lately this spate of violence against foreigners…… if this continues, there is likely to be a backlash and a steady exodus of multinational giants towards more pleasant, peaceful havens…The government of Karnataka must act immediately to stem the flow of such stupid, racist attacks on foreigners because they are foreigners The rabble rousing troublemakers must be brought to book and severely punished..
With many Indians, I apologise profusely to the attacked lady for the treatment meted out to her…..and I hope she will recover fully physically and morally from the shameful attack……I haven’t heard or seen any apology from the local government nor from the central government as yet….but I do hope that there will be an official reaction to this racist attack.