Skip to content
Advertisements

CSIR’s new patented Clot buster, PEGylated Streptokinase will revolutionize treatment of Strokes

Newsroom24x7 Network

New Delhi: A new Clot buster, PEGylated Streptokinase – a Novel Biological Entity developed by Dr. Girish Sahni, DG, CSIR and Secretary, DSIR and his team of inventors at CSIR-Institute of Microbial Technology (CSIR-IMTECH), Chandigarh is all set to revolutionize the treatment of ischemic strokes. Ischemic stroke is a condition caused by a dysfunction in the supply of blood to the brain due to emboli, thrombus or atherosclerosis occurring in cerebral arteries. According to the American Stroke Association (ASA), brain strokes are the second leading cause of death in the world with a staggering 15 million people effected causing 11 million people either die or become permanently disabled. Surprisingly, the prevalence of stroke is much higher in India than the West and about 87% of all strokes are ischemic strokes.

Dr. Anil Koul, Director, CSIR-IMTECH, Dr. Girish Sahni, DG, CSIR and Debayan Ghosh, President, Epygen

CSIR-IMTECH and Epygen Biotech Pvt. Ltd., Mumbai, have entered into an agreement for the latter to develop PEGylated Streptokinase for treatment of Ischemic Stroke.Epygen is the first company in India with exclusive license of this Novel Biological Entity (NBE) thrombolytic protein for ischemic stroke. Epygen Biotech Pvt Ltd is a biopharmaceutical company, engaged in research and manufacturing of Therapeutic Proteins for Oncology, Cardiovascular and Immune disorders.

PEGylated Streptokinase, the novel recombinant protein Thrombolytic molecule has been precisely engineered through decades of research for enhanced proteolytic stability and extended plasma half-life, fibrin-specificity and associated clot specificity, with reduced immuno-reactivity which would be significant attributes with unmistakable clinical advantages such as reduced probability of hemorrhage over current treatment regimens of thrombolytic drugs for acute stroke. These are huge advantages with a potential to transform the way ischemic stroke, deep-vein thrombosis, pulmonary embolism and acute myocardial infarction are treated around the globe, especially in the developing world.

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google+ photo

You are commenting using your Google+ account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

This site uses Akismet to reduce spam. Learn how your comment data is processed.

%d bloggers like this: